Cholesterol Calculator

A lipid panel reports four numbers: total cholesterol, HDL, triglycerides, and (sometimes) LDL. Our cholesterol calculator computes LDL using the Friedewald equation if it's not directly measured, derives non-HDL cholesterol (which captures all the atherogenic particles), and calculates the total/HDL and LDL/HDL ratios. It then classifies each value against the NCEP ATP III categories — Optimal, Near Optimal, Borderline High, High — and synthesizes them into an overall risk picture. Use it to understand a lab report, track changes over time, and see how each component contributes to your cardiovascular risk profile.

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science Lipid Panel (mg/dL)

Leave 0 to compute via Friedewald

analytics Lipid Analysis

Overall Risk
Moderate Risk
Total 210 · Borderline High
LDL 130 · Borderline High
HDL 50 · Average
Triglycerides 150 · Borderline High
Non-HDL
160
TC/HDL
4.20
LDL/HDL
2.60
Interpretation
Multiple lipid abnormalities — consider lifestyle changes and discuss with doctor

tips_and_updates Tips

  • Total cholesterol: <200 desirable, 200-239 borderline, ≥240 high
  • LDL: <100 optimal, 100-129 near optimal, 130-159 borderline, 160-189 high, ≥190 very high
  • HDL: <40 low (risk factor), 40-59 average, ≥60 protective
  • Triglycerides: <150 normal, 150-199 borderline, 200-499 high, ≥500 very high
  • Non-HDL = total − HDL is more reliable than LDL when triglycerides are elevated
  • Total/HDL ratio under 3.5 is desirable; under 5 is acceptable
  • Lifestyle (Mediterranean diet, exercise, weight loss) can drop LDL by 20-30%

functions Formula

{LDL (Friedewald) = Total − HDL − Triglycerides/5 (valid if TG < 400) [{Total Cholesterol Sum of all cholesterol particles} {HDL High-density lipoprotein — protective ('good')} {LDL Low-density lipoprotein — atherogenic ('bad')} {Triglycerides Fat circulating in blood, often diet-related} {Non-HDL Total − HDL = sum of all atherogenic particles} {Total/HDL Ratio Lower is better; <3.5 desirable} {LDL/HDL Ratio Lower is better; <2.5 desirable}] The Friedewald equation estimates LDL when it's not directly measured. It assumes triglycerides and VLDL are in a fixed ratio, which breaks down when triglycerides exceed 400 mg/dL. Non-HDL cholesterol is increasingly used because it captures all atherogenic lipoproteins (LDL + VLDL + IDL + Lp(a)) and is reliable even with high triglycerides. NCEP ATP III categories are the standard framework for interpreting lipid values.}

science Example: Borderline lipid panel

LDL via Friedewald = 210 − 50 − 150/5 = 130 mg/dL. Non-HDL = 210 − 50 = 160. Total/HDL ratio = 4.2 (above the desirable 3.5). All values are borderline high — none catastrophic individually, but combined they put this person in a moderate-risk category. Lifestyle changes (diet, exercise) should be the first intervention.

Expected Results

Overall Risk Moderate Risk
LDL 130
Non-HDL Cholesterol 160
Total/HDL Ratio 4.2
LDL/HDL Ratio 2.6
Total Category Borderline High
LDL Category Borderline High
HDL Category Average
Triglycerides Category Borderline High

How to Use This Calculator

1

Enter total cholesterol

Input total cholesterol from your lab report.

2

Enter HDL

Provide HDL (high-density lipoprotein).

3

Enter LDL or leave blank

Input LDL if measured, or leave 0 to calculate via Friedewald.

4

Enter triglycerides

Provide triglycerides.

5

Read interpretation

Review LDL, non-HDL, ratios, and category for each value.

The Formula

The Friedewald equation estimates LDL when it's not directly measured. It assumes triglycerides and VLDL are in a fixed ratio, which breaks down when triglycerides exceed 400 mg/dL. Non-HDL cholesterol is increasingly used because it captures all atherogenic lipoproteins (LDL + VLDL + IDL + Lp(a)) and is reliable even with high triglycerides. NCEP ATP III categories are the standard framework for interpreting lipid values.

LDL (Friedewald) = Total − HDL − Triglycerides/5 (valid if TG < 400)

lightbulb Variables Explained

  • Total Cholesterol Sum of all cholesterol particles
  • HDL High-density lipoprotein — protective ('good')
  • LDL Low-density lipoprotein — atherogenic ('bad')
  • Triglycerides Fat circulating in blood, often diet-related
  • Non-HDL Total − HDL = sum of all atherogenic particles
  • Total/HDL Ratio Lower is better; <3.5 desirable
  • LDL/HDL Ratio Lower is better; <2.5 desirable

tips_and_updates Pro Tips

1

Total cholesterol: <200 desirable, 200-239 borderline, ≥240 high

2

LDL: <100 optimal, 100-129 near optimal, 130-159 borderline, 160-189 high, ≥190 very high

3

HDL: <40 low (risk factor), 40-59 average, ≥60 protective

4

Triglycerides: <150 normal, 150-199 borderline, 200-499 high, ≥500 very high

5

Non-HDL = total − HDL is more reliable than LDL when triglycerides are elevated

6

Total/HDL ratio under 3.5 is desirable; under 5 is acceptable

7

Lifestyle (Mediterranean diet, exercise, weight loss) can drop LDL by 20-30%

A 'good' cholesterol report needs all four metrics in healthy ranges, not just total cholesterol. Two people can have identical total cholesterol of 200 but very different cardiovascular risk depending on their HDL and triglycerides. High HDL with moderate LDL is much safer than low HDL with the same LDL. Modern guidelines emphasize the full panel and derived metrics like non-HDL and the total/HDL ratio over total cholesterol alone.

The Friedewald equation assumes a fixed ratio of triglycerides to VLDL cholesterol. This works well when triglycerides are below 400 mg/dL, which covers the vast majority of patients. Above 400, the equation overestimates VLDL and underestimates LDL. In those cases, labs use direct LDL measurement or non-HDL cholesterol as the primary metric. If your triglycerides are above 400, prefer the directly measured LDL or non-HDL value.

Frequently Asked Questions

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All formulas verified against official standards.